All IL-6 reagents are produced in house and quality controlled, including 22 IL-6 Antibody, 2 IL-6 ELISA, 61 IL-6 Gene, 1 IL-6 IPKit, 6 IL-6 Protein, 3 IL-6 qPCR. All IL-6 reagents are ready to use.
Recombinant IL-6 proteins are expressed by E. coli with fusion tags as Native.
IL-6antibodies are validated with different applications, which are WB, ELISA, IP, ELISA(Det), Neutralization, ELISA(Cap), IHC-P.
IL-6cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each IL-6 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
IL-6ELISA Kit are quality controlled by 8 internation QC standard which guarantee every ELISA Kit with high quality.
Interleukin-6 (IL-6) is a multifunctional α-helical cytokine that regulates cell growth and differentiation of various tissues, which is known particularly for its role in the immune response and acute phase reactions. IL-6 protein is secreted by a variety of cell types including T cells and macrophages as phosphorylated and variably glycosylated molecule. It exerts actions through the its heterodimeric receptor composed of IL-6R that lacks the tyrosine/kinase domain and binds IL-6 with low affinity, and ubiquitously expressed glycoprotein 130 (gp130) that binds the IL-6. IL-6R complex with high affinity and thus transduces signals. IL-6 is also involved in hematopoiesis, bone metabolism, and cancer progression, and has been defined an essential role in directing transition from innate to acquired immunity.