All FCRL1 reagents are produced in house and quality controlled, including 4 FCRL1 Antibody, 24 FCRL1 Gene, 1 FCRL1 IPKit, 2 FCRL1 Lysate, 2 FCRL1 Protein, 2 FCRL1 qPCR. All FCRL1 reagents are ready to use.
Recombinant FCRL1 proteins are expressed by HEK293 Cells with fusion tags as C-His.
FCRL1antibodies are validated with different applications, which are WB, ELISA, IP.
FCRL1cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each FCRL1 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
Fc receptor-like protein 1, also known as FcR-like protein 1, Fc receptor homolog 1, IFGP family protein 1, Immune receptor translocation-associated protein 5 and FCRL1, is a single-pass type I membrane protein which contains three Ig-like C2-type (immunoglobulin-like) domains. It is a cell-surface membrane protein belonging to FCRL family and is preferentially expressed on B cells. FCRL1 is primarily expressed in secondary lymphoid tissues by mature subsets of B cells. It is detected in spleen, lymph node, heart, skeletal muscle, kidney, liver and placenta. FCRL1 is specifically expressed by mature B lineage cells with higher expression in naive versus memory B cells (at protein level). Human Fc receptor-like molecules (FCRL1, FCRL2, FCRL3, FCRL4, FCRL5) have tyrosine-based immunoregulatory potential and are expressed by B-lineage subpopulations. FCRL1 may function as an activating coreceptor in B cells. It may also function in B cells activation and differentiation.