All CD52 reagents are produced in house and quality controlled, including 48 CD52 Gene, 3 CD52 Lysate, 3 CD52 Protein, 3 CD52 qPCR. All CD52 reagents are ready to use.
Recombinant CD52 proteins are expressed by HEK293 Cells with fusion tags as C-human IgG1-Fc.
CD52cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each CD52 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
CD52 / CDW52 is a small glycosylphosphatidylinositol (GPI) anchored glycoprotein. It has a mature peptide comprising only 12 amino acids and is abundantly expressed on human lymphocytes. From the clinical point of view this protein is an important target for therapeutic interventions aimed at leukocyte depletion in hematological malignancies and post-transplant immunosuppression. CD52 / CDW52 may play a role in carrying and orienting carbohydrate. It is an unusually good target for complement-mediated cell lysis.