All CD32 reagents are produced in house and quality controlled, including 8 CD32 Antibody, 12 CD32 Gene, 3 CD32 Lysate, 3 CD32 Protein, 1 CD32 qPCR. All CD32 reagents are ready to use.
Recombinant CD32 proteins are expressed by HEK293 Cells with fusion tags as C-His, C-AVI & His.
CD32antibodies are validated with different applications, which are FCM, ELISA.
CD32cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each CD32 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
Expression host: HEK293 Cells
Receptors for Fc portion of IgG (Fcγ Rs) are members of the Ig superfamily, and are divided into three classes designated Fcγ RI (CD64), Fcγ RII (CD32), and Fcγ RIII (CD16). CD32 protein is a low affinity receptor for IgG that binds only IgG immune complexes and is expressed on a diverse range of cells such as monocytes, macrophages, neutrophils, eosinophils, platelets, and B cells. Human CD32 class is encoded by three closely related genes, and designated Fcγ RII A, B, and C which share 94-99% amino acid identity in their extracellular domains but differ substantially in their transmembrane and cytoplasmic domains. CD32 is involved in a number of immune responses including antibody-dependent cell-mediated cytotoxicity, clearance of immune complexes, release of inflammatory mediators, and regulation of antibody production.