All CD19 reagents are produced in house and quality controlled, including 11 CD19 Antibody, 1 CD19 ELISA, 30 CD19 Gene, 2 CD19 IPKit, 4 CD19 Lysate, 2 CD19 Others, 4 CD19 Protein, 2 CD19 qPCR. All CD19 reagents are ready to use.
Recombinant CD19 proteins are expressed by HEK293 Cells with fusion tags as C-His, C-human IgG1-Fc.
CD19antibodies are validated with different applications, which are FCM, IHC-P, ELISA, IP, ELISA(Det), ELISA(Cap).
CD19cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each CD19 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
CD19ELISA Kit are quality controlled by 8 internation QC standard which guarantee every ELISA Kit with high quality.
The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cluster of differentiation 19 (CD19) is a member of CD system. CD19 is a cell surface molecule that assembles with the antigen receptor of B-cells. This results in a descent in threshold for antigen receptor-dependent stimulation. A simplified view holds that the ability of B-cells to respond to the various antigens in a specific and sensitive manner is achieved in the presence of low-affinity antigen receptors. CD19 primarily acts as a B-cell coreceptor in conjunction with CD21 and CD81. The formation of the receptor complex is induced by antigen and CD19, induced by exogenous antigen, has been found cytoplasmic tail phosphorylated and bind to sIg.